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A Cluster analysis on MDR-TB treatment outcomes.

Author

Jayson  E. Cinense

Related Institution

College of Nursing - Cebu Normal University

Publication Information

Publication Type
Thesis/Dissertations
Thesis Degree
MS
Specialization
Medical - Surgical Nursing
Publication Date
September 2014

Abstract

Multidrug-resistant tuberculosis has become a fast growing problem worldwide. According to Gler et al. (2011), the Philippines ranks fifth among 27 priority countries for MDR-TB. This study aimed to determine the characteristics of MDR-TB patients clustered according to treatment outcomes. The study utilized non-experimental, ex post facto design involving retrospective approach. Patients with a laboratory-confirmed MDR-TB and who received a treatment regimen between September 2008 and December 2011 were included in the study. A researcher-made data collection guide was used to obtain the socio-demographic data, socio-economic data, history of substance use, co-morbidities and treatment outcome of patients from patients' medical records. Among the 160 patients identified, 58.1% had an unsuccessful outcome while the success rate is 41.9%. The default rate was considerably high that comprised of 41.9% among the 58.1% who had unsuccessful outcomes. The forced cluster analysis indicated that the characteristics of MDR-TB patients with successful and unsuccessful treatment outcome produced broadly comparable results while most differences between two outcomes were relatively small.  Further analysis showed that there was no significant difference between the treatment outcomes and all the variables identified in the present study at p

References

1. Padua, R , Tumapon, T , Lerin, M . "Graduate Education Policy Framework forDeveloping Countries: Survey and Cluster Analysis of Worldwide Patterns inAdvanced Education" SMC Research Journal , 2007. Retrieved from: http://research.smciligan.edu.ph
2. Tupasi, T , Gupta, R , Quelapio, M , Orillaza, R B, Mira, N R, Mangubat, N , Floyd, K . "Feasibility and Cost-Effectiveness of Treating Multidrug-Resistant Tuberculosis: A Cohort Study in the Philippines" PLoS Med 3(9): e352, . Retrieved from: http://doi:10.1371/journal.pmed.0030352
3. Tupasi, T , Quelapio, M I, Orillaza, R B, Alcantara, C , Mira, N R, Abeleda, M R. "DOTS-Plus for MultiDrug-Resistant Tuberculosis in the Philippines: Global Assistance Urgently needed" Turbeculosis (Edinb) 83((1-3)): 52-8, . Retrieved from: http://www.ncbi.nlm.nih.gov

Physical Location

LocationLocation CodeAvailable FormatAvailability
Cebu Normal University T C574 2014 Abstract Print Format

 
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